Our complex Chemical team delivers on more custom, large scale and more complex projects. This includes both Biosynth’s own Bulk and Custom products and those of their CDMO customers, making the most of the company’s expanding manufacturing sites. Our teams maintain long-term relationships with our clients. We pride ourselves at Biosynth in taking on the most complex challenges in chemistry and solving the problems that no one else can. Our teams of synthetic chemists and production staff are uniquely skilled and able to work very flexibly across different areas of our product lines. As the CDMO business has expanded, our flexible way of working has really benefitted customers. Clients can utilize either Biosynth’s entire end-to-end service offering or pick out the aspects that they need at the time they need them. We’ve had projects that are taken right through from early development and seen into the GMP suite and others in which we have simply transferred in a process, made some small improvements and scaled for large-scale manufacturing at ton scale.
We work on the principle that no chemistry is too hard for us - if we don’t have a compound, we’ll make it. We specialize in the chemistry of carbohydrates, nucleosides and enzyme substrates, both in our catalog research products and in our bulk and custom business. We also have a huge range across antimicrobials, natural products, impurities, intermediates and building blocks.
Biosynth provide custom synthesis solutions tailored to meet our needs. Our synthetic laboratories operate from modern facilities based in the United Kingdom, Switzerland, Slovakia and China. Our scientists are predominantly Ph.D.-qualified and have extensive industry experience in carbohydrates, imino sugars, glycosylations, nucleosidations and medicinal chemistry.
Our state of the art synthetic labs are equipped with modern preparative and analytical tools:
⋅ Nuclear Magnetic Resonance (NMR) 400 MHz
with Broadband Probe
⋅ Liquid Chromatography–Mass Spectrometry
(LC-MS)
⋅ Medium Pressure Liquid Chromatography
(MPLC)
⋅ Size Exclusion Chromatography (SEC)
⋅ Preparative HPLC
⋅ Microwave Synthesis System
⋅ Automated Purification Systems (Puriflash,
Biotage and Companion)
⋅ Rotavapors and Freeze Dryers
⋅ Ultra Performance Liquid Chromatography
(UPLC)
⋅ Ion Chromatography (IC) system Dionex
⋅ Gas chromatography (GC)
⋅ Inductively Coupled Plasma (ICP) for Metal
Ion Analysis
⋅ Polarimeter for Optical Rotation
Measurements
We specialize in the following chemistries:
⋅ Functionalized Carbohydrate Building Blocks
and Derivatives
⋅ Oligosaccharide Synthesis
⋅ Nucleosides, Dinucleotides and Analogues
⋅ Heterocyclic Chemistry
⋅ Novel Enzyme Substrates
⋅ Natural Product Synthesis
⋅ Impurities and Metabolites
⋅ Protein Conjugation, Biotin and Click Linkers
⋅ Fluorination, Phosphorylation and Sulphation
Chemistry
⋅ High Purity Complex Products
⋅ Synthetic Route Development
⋅ Regulated Materials
⋅ Our State-of-the-Art Synthetic Labs are
Equipped with Modern Preparative and
Analytical Tools
Terms of service:
⋅ Small-Scale to Bulk Quantities
⋅ Experienced Chemists, Predominantly Ph.D.
- Qualified
⋅ Timeliness
⋅ Confidentiality
⋅ ISO-Certified Quality Management System
- ISO 9001:2015
Our custom synthesis laboratories are headquartered in the United Kingdom and we also have laboratories in Switzerland, Slovakia and China. High quality, on-time delivery and confidentiality are at the core of our service.
Large Scale Manufacture:
We manufacture a variety of product types that are applicable for pharmaceutical, diagnostic, analytical and research purposes from small-scale to large-scale. Our team of highly experienced chemists and technicians allow for flexibility in the quantities of products that can be manufactured.
Product Applications:
⋅ Carbohydrate-Based Drugs
⋅ Carbohydrate-Based Detergents
⋅ Antiviral Nucleoside Analogues
⋅ Substrates for Detection of Enzymatic Activity
⋅ Food and Environmental Analytical Compounds
⋅ Cosmetic Ingredients
⋅ Nutraceutical Ingredients